{"title":"Research Support Compounds","description":"\u003cp\u003eFind the research support compounds and laboratory materials available alongside the Bulk Peptides peptide catalog. Compare the listed identity, formulation, and presentation for each product.\u003c\/p\u003e\u003cp\u003eFor mixtures or materials with a specific analytical requirement, review the product details and request the relevant documentation before selecting supplies for your research workflow.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/strong\u003e\u003c\/p\u003e","products":[{"product_id":"ll-37","title":"LL-37","description":"\u003ch2\u003eLL-37 Research Peptide\u003c\/h2\u003e\u003cp\u003eExplore LL-37 from the Bulk Peptides research catalog. This peptide is offered for qualified laboratory work; compare the available presentation with the identity and documentation requirements of your project.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"\/pages\/ll-37-research-guide\"\u003eRead the LL-37 research guide\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eLL-37 is a synthetic peptide with the molecular formula \u003cstrong\u003eC₂₀₅H₃₄₀N₆₀O₅₃\u003c\/strong\u003e. It corresponds to the C-terminal sequence of the endogenous human cathelicidin antimicrobial protein (hCAP18). In aqueous laboratory environments, the peptide adopts a highly amphipathic alpha-helical structure. This distinct conformation is critical for its biological activity, as it allows the peptide to seamlessly interface with the lipid bilayers of cellular membranes.\u003c\/p\u003e\n\u003cp\u003eScientific studies focus extensively on the peptide’s ability to selectively disrupt microbial membranes. Driven by its net positive charge (cationic nature), LL-37 binds to the negatively charged surface molecules of various pathogens. In vitro assays demonstrate that this interaction leads to the formation of transmembrane pores and subsequent cell lysis. Researchers utilize this mechanism to study the innate immune system’s initial defense response against bacterial, viral, and fungal agents independently of traditional antibiotic pathways.\u003c\/p\u003e\n\u003cp\u003eBeyond its direct antimicrobial activity, LL-37 is investigated for its complex immunomodulatory signaling. In cellular models, the peptide has been observed to neutralize endotoxins such as lipopolysaccharides (LPS), thereby downregulating the release of pro-inflammatory cytokines and mitigating hyper-inflammatory responses. Furthermore, researchers examine its role in extracellular matrix remodeling and angiogenesis, utilizing murine models to understand how host defense peptides may accelerate epithelial cell migration and wound closure under induced metabolic stress.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eScott, M. G., et al. (2002). “The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses.” \u003cem\u003eThe Journal of Immunology\u003c\/em\u003e, 169(7), 3883-3891.\u003c\/li\u003e\n\u003cli\u003eDürr, U. H., et al. (2006). “LL-37, the only human member of the cathelicidin family of antimicrobial peptides.” \u003cem\u003eBiochimica et Biophysica Acta (BBA)-Biomembranes\u003c\/em\u003e, 1758(9), 1408-1425.\u003c\/li\u003e\n\u003cli\u003eNijnik, A., \u0026amp; Hancock, R. E. (2009). “The roles of cathelicidin LL-37 in immune defences and novel clinical applications.” \u003cem\u003eCurrent Opinion in Hematology\u003c\/em\u003e, 16(1), 41-47.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"5 MG","offer_id":51303542128807,"sku":null,"price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/ll-37.png?v=1788656407"},{"product_id":"lipo-c-fb","title":"Lipo-C (FB)","description":"\u003ch2\u003eLipo-C (FB) Research Compound\u003c\/h2\u003e\u003cp\u003eLipo-C (FB) is a multi-component research formulation in the Bulk Peptides catalog. Review its product-specific composition and presentation; Lipo-C formulations can differ, and the FB listing should be evaluated on its own specifications.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"\/pages\/lipo-c-research-guide\"\u003eRead the Lipo-C (FB) research guide\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eThe LC526 Lipo-C formulation, commonly referred to in research settings as the “FB” blend, is a specialized compound mixture containing six primary active ingredients: \u003cstrong\u003eL-Carnitine\u003c\/strong\u003e, \u003cstrong\u003eMethionine\u003c\/strong\u003e, \u003cstrong\u003eInositol\u003c\/strong\u003e, \u003cstrong\u003eCholine\u003c\/strong\u003e, \u003cstrong\u003eVitamin B12\u003c\/strong\u003e, and \u003cstrong\u003eVitamin B6 (Pyridoxine)\u003c\/strong\u003e. This expanded blend is frequently utilized in laboratory environments to study advanced metabolic processes, specifically focusing on mitochondrial bioenergetics and the mobilization of adipose tissue in murine models.\u003c\/p\u003e\n\u003cp\u003eScientific investigation into this specific matrix focuses on the complementary roles of its constituents. L-Carnitine acts as the primary transporter, essential for shuttling long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation. Concurrently, Methionine, Inositol, and Choline are investigated as lipotropic agents. Researchers study these molecules for their ability to influence hepatic lipid export, structural cell membrane integrity, and the prevention of lipid accumulation (steatosis) in liver tissue models.\u003c\/p\u003e\n\u003cp\u003eThe addition of Vitamin B12 and Vitamin B6 differentiates this blend by introducing critical enzymatic cofactors into the experimental environment. Vitamin B12 is required for the function of methionine synthase, linking it directly to the methylation cycle, while Vitamin B6 is heavily involved in amino acid metabolism and the transsulfuration pathway. Current studies examine whether the simultaneous administration of these six compounds exerts a profound synergistic effect on enhancing overall metabolic efficiency and regulating energy homeostasis.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eRebouche, C. J. (2004). “Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism.” \u003cem\u003eAnnals of the New York Academy of Sciences\u003c\/em\u003e, 1033(1), 30-41.\u003c\/li\u003e\n\u003cli\u003eZeisel, S. H., \u0026amp; Blusztajn, J. K. (1994). “Choline and human nutrition.” \u003cem\u003eAnnual Review of Nutrition\u003c\/em\u003e, 14(1), 269-296.\u003c\/li\u003e\n\u003cli\u003eKennedy, D. O. (2016). “B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review.” \u003cem\u003eNutrients\u003c\/em\u003e, 8(2), 68.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"10 ML","offer_id":51303542227111,"sku":null,"price":92.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/lipo-c-fb.png?v=1788657625"},{"product_id":"shb","title":"SHB","description":"\u003ch2\u003eSHB Research Compound\u003c\/h2\u003e\u003cp\u003eSHB is offered as a multi-component laboratory research material. Review the composition and available product information for this formulation before comparing it with other compound mixtures.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eSHB is an advanced research compound mixture comprising a precisely measured matrix of nine biochemicals. The formulation includes L-Arginine, L-Ornithine, L-Citrulline, L-Lysine, L-Glutamine, L-Proline, L-Taurine, L-Carnitine, and N-Acetylcysteine (NAC). Rather than examining a single pathway, researchers utilize this extensive blend to observe complex, multi-system cellular responses, particularly focusing on how combined amino acid substrates influence energy homeostasis and structural tissue repair in cellular models.\u003c\/p\u003e\n\u003cp\u003eA primary area of scientific investigation with this blend centers on the urea cycle and nitric oxide (NO) synthesis. The inclusion of L-Arginine, L-Citrulline, and L-Ornithine provides overlapping precursor pathways for the production of NO, a critical signaling molecule involved in endothelial function and vasodilation. By supplying these precursors simultaneously, laboratory models can be used to study maximized enzymatic kinetics within the endothelium and observe the subsequent downstream effects on cellular respiration and waste metabolite clearance.\u003c\/p\u003e\n\u003cp\u003eFurthermore, the blend is heavily investigated for its impact on cellular defense and mitochondrial efficiency. N-Acetylcysteine (NAC) acts as a direct precursor to glutathione, the primary intracellular antioxidant, allowing researchers to study the mitigation of reactive oxygen species (ROS) in tissue samples. Concurrently, L-Carnitine and L-Taurine are examined for their roles in fatty acid transport across the mitochondrial membrane and cellular osmoregulation, respectively. Along with structural amino acids like L-Proline, L-Lysine, and L-Glutamine, the formulation provides a complete substrate profile for studying extracellular matrix remodeling and muscle cell recovery post-exertion in animal models.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eWu, G., \u0026amp; Meininger, C. J. (2000). “Arginine nutrition and cardiovascular function.” \u003cem\u003eJournal of Nutrition\u003c\/em\u003e, 130(11), 2626-2629.\u003c\/li\u003e\n\u003cli\u003eKerksick, C., \u0026amp; Willoughby, D. (2005). “The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress.” \u003cem\u003eJournal of the International Society of Sports Nutrition\u003c\/em\u003e, 2(2), 38-44.\u003c\/li\u003e\n\u003cli\u003eRebouche, C. J. (2004). “Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism.” \u003cem\u003eAnnals of the New York Academy of Sciences\u003c\/em\u003e, 1033(1), 30-41.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"10 MG","offer_id":51303542259879,"sku":null,"price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/shb.png?v=1788658061"},{"product_id":"aicar-50mg","title":"AICAR 50mg","description":"\u003ch2\u003eAICAR 50mg Research Compound\u003c\/h2\u003e\u003cp\u003eAICAR is offered as a 50mg laboratory research compound. This listing belongs to the research-compound catalog; consult the supporting evidence guide and product information for your analytical review.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"\/pages\/aicar-research-guide\"\u003eRead the AICAR 50mg research guide\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003ch3\u003eAICAR 50mg research compound\u003c\/h3\u003e\n\u003cp\u003eAICAR is supplied as a 50mg laboratory reference material for controlled biochemical and analytical workflows.\u003c\/p\u003e\n\u003ch3\u003eProduct details\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAmount: 50mg\u003c\/li\u003e\n\u003cli\u003eFormat: laboratory research material\u003c\/li\u003e\n\u003cli\u003eCatalog group: research support compounds\u003c\/li\u003e\n\u003cli\u003eHandling: use suitable protective equipment and follow the product label for storage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e This material is intended for qualified laboratory research. It is not a drug, food, cosmetic, or medical product and is not for human or veterinary use.\u003c\/p\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"50 MG","offer_id":51303542423719,"sku":"BP-AICAR-50","price":72.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/aicar-50mg.png?v=1788657634"},{"product_id":"slu-pp332","title":"SLU PP332","description":"\u003ch2\u003eSLU-PP-332 Research Compound\u003c\/h2\u003e\u003cp\u003eSLU-PP-332 is offered as a laboratory research compound. It is a small-molecule material rather than an amino-acid peptide; use its product-specific information when reviewing the catalog for your experiment.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"\/pages\/slu-pp-332-research-guide\"\u003eRead the SLU PP332 research guide\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eSLU-PP-332 is a synthetic compound with the molecular formula \u003cstrong\u003eC₁₈H₁₄N₂O₂\u003c\/strong\u003e. It is distinct from amino acid-based peptides, functioning instead as a direct nuclear receptor agonist. It was developed to probe the physiological roles of Estrogen-Related Receptors (ERRs), which are orphan nuclear receptors involved in the regulation of cellular energy metabolism.\u003c\/p\u003e\n\u003cp\u003ePrimary research focuses on the interaction between SLU-PP-332 and the ERRα, ERRβ, and ERRγ receptors. Upon binding, SLU-PP-332 is observed to stabilize the active conformation of these receptors, promoting the recruitment of coactivators such as PGC-1α (Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha).\u003c\/p\u003e\n\u003cp\u003eIn laboratory studies involving murine models, SLU-PP-332 has been investigated for its ability to enhance mitochondrial respiration. Data indicates that the compound may upregulate the expression of genes associated with oxidative phosphorylation and fatty acid metabolism. Researchers have noted that administration in mice resulted in an increase in type IIa oxidative muscle fibers, leading to the classification of this compound as an “exercise mimetic” in scientific literature.\u003c\/p\u003e\n\u003cp\u003eFurther investigation suggests that SLU-PP-332 may influence lipid metabolism. Studies utilizing diet-induced obese mice have observed changes in energy expenditure and fat mass accumulation without alterations in food intake or physical activity levels. These findings suggest a potential pathway for modulating metabolic profiles through direct receptor activation.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eBillon, C., et al. (2023). “Synthetic ERRα\/β\/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.” \u003cem\u003eACS Chemical Biology\u003c\/em\u003e, 18(4), 756-771. \u003ca href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.3c00205\" target=\"_blank\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eBillon, C., et al. (2024). “A Synthetic ERR Agonist Alleviates Metabolic Syndrome.” \u003cem\u003eJournal of Pharmacology and Experimental Therapeutics\u003c\/em\u003e, 388(2), 232-240. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37739818\/\" target=\"_blank\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eFan, W., \u0026amp; Evans, R. M. (2015). “Exercise Mimetics: Impact on Health and Performance.” \u003cem\u003eCell Metabolism\u003c\/em\u003e, 22(3), 399-413. \u003ca href=\"https:\/\/www.cell.com\/cell-metabolism\/fulltext\/S1550-4131(15)00393-2\" target=\"_blank\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"5 MG","offer_id":51303542587559,"sku":"SLUPP33210","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/slu-pp332.png?v=1788657802"},{"product_id":"lipo-c","title":"Lipo-C","description":"\u003ch2\u003eLipo-C Research Compound\u003c\/h2\u003e\u003cp\u003eLipo-C is offered as a multi-component laboratory research material. Compare its listed formulation and presentation with your project requirements; similarly named Lipo-C products can contain different component combinations.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"\/pages\/lipo-c-research-guide\"\u003eRead the Lipo-C research guide\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eLipo-C is a research compound mixture containing four primary active ingredients: \u003cstrong\u003eL-Carnitine (C₇H₁₅NO₃)\u003c\/strong\u003e, \u003cstrong\u003eMethionine (C₅H₁₁NO₂S)\u003c\/strong\u003e, \u003cstrong\u003eInositol (C₆H₁₂O₆)\u003c\/strong\u003e, and \u003cstrong\u003eCholine (C₅H₁₄NO)\u003c\/strong\u003e. This blend is frequently utilized in laboratory settings to study metabolic processes, specifically mitochondrial bioenergetics and the mobilization of adipose tissue in murine models.\u003c\/p\u003e\n\u003cp\u003eScientific investigation into the components of Lipo-C focuses on their individual and collective roles. L-Carnitine is studied for its essential role in transporting long-chain fatty acids across the mitochondrial membrane for beta-oxidation. Methionine, an essential amino acid, acts as a lipotropic agent and a precursor for glutathione, a major antioxidant. Research suggests Methionine may influence hepatic lipid export.\u003c\/p\u003e\n\u003cp\u003eThe other components, Inositol and Choline, are investigated for their roles in cell signaling and structural integrity. Choline is a precursor for phosphatidylcholine and acetylcholine, while Inositol is involved in insulin signal transduction. Current studies examine whether the co-administration of these four compounds exerts a synergistic effect on preventing lipid accumulation in the liver (hepatic steatosis) and enhancing metabolic efficiency in test subjects.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eRebouche, C. J. (2004). “Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism.” \u003cem\u003eAnnals of the New York Academy of Sciences\u003c\/em\u003e, 1033(1), 30-41.\u003c\/li\u003e\n\u003cli\u003eZeisel, S. H., \u0026amp; Blusztajn, J. K. (1994). “Choline and human nutrition.” \u003cem\u003eAnnual Review of Nutrition\u003c\/em\u003e, 14(1), 269-296.\u003c\/li\u003e\n\u003cli\u003eMato, J. M., et al. (2002). “S-Adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.” \u003cem\u003eJournal of Hepatology\u003c\/em\u003e, 30(6), 1081-1089.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"10 ML","offer_id":51303542751399,"sku":"LIPOC10ML","price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/lipo-c.png?v=1788657109"},{"product_id":"vitamin-b12","title":"Vitamin B12","description":"\u003ch2\u003eVitamin B12 Research Compound\u003c\/h2\u003e\u003cp\u003eVitamin B12 is available as a laboratory research compound, with the current product description identifying methylcobalamin. Check the listed presentation and the documentation relevant to your analytical requirements.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eMethylcobalamin is a specific form of Vitamin B12 with the molecular formula \u003cstrong\u003eC₆₃H₉₁CoN₁₃O₁₄P\u003c\/strong\u003e. Structurally, it consists of a corrin ring surrounding a central cobalt ion. In this specific configuration, the ligand attached to the cobalt is a methyl group, distinguishing it from other forms like Cyanocobalamin or Hydroxocobalamin. This structural difference allows Methylcobalamin to participate directly in methyl-group transfer reactions without the need for metabolic conversion.\u003c\/p\u003e\n\u003cp\u003eScientific interest in Methylcobalamin centers on its role as a cofactor for the cytosolic enzyme methionine synthase. This enzyme is responsible for catalyzing the remethylation of homocysteine to methionine, an essential amino acid. By modulating this pathway, researchers investigate the compound’s influence on cellular DNA synthesis and the regulation of homocysteine levels, which are markers often associated with vascular and endothelial health in research models.\u003c\/p\u003e\n\u003cp\u003eIn neurobiological research, Methylcobalamin is studied for its potential effects on the nervous system. Animal studies have explored its involvement in the synthesis of neuronal lipids and the maintenance of the myelin sheath. Furthermore, investigations utilize this compound to observe its impact on nerve regeneration and axonal transport in models of peripheral neuropathy.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eZhang, Y., et al. (2013). “Methylcobalamin: A Potential Vitamin of Pain Modulation.” \u003cem\u003eNeural Plasticity\u003c\/em\u003e, 2013, 424651.\u003c\/li\u003e\n\u003cli\u003eTakahashi, K., et al. (2005). “Methylcobalamin increases Erk1\/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model.” \u003cem\u003eExperimental Neurology\u003c\/em\u003e, 192(2), 289-299.\u003c\/li\u003e\n\u003cli\u003eWolffenbuttel, B. H. R., et al. (2019). “The Many Faces of Cobalamin (Vitamin B12) Deficiency.” \u003cem\u003eMayo Clinic Proceedings: Innovations, Quality \u0026amp; Outcomes\u003c\/em\u003e, 3(2), 200-214.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"10 MG","offer_id":51303542980775,"sku":"B1210ML","price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/vitamin-b12.png?v=1788658160"},{"product_id":"reconstitution-solution-10ml-2-pack","title":"Reconstitution Solution 10ml 2-Pack","description":"\u003ch2\u003eReconstitution Solution: Two 10mL Vials\u003c\/h2\u003e\u003cp\u003eThis laboratory-solution pack contains two separately closed 10mL vials.\u003c\/p\u003e\u003ch3\u003ePackage and labeled formulation\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eTwo 10mL glass vials per pack.\u003c\/li\u003e\n\u003cli\u003eLabeled formulation: 0.9% benzyl alcohol.\u003c\/li\u003e\n\u003cli\u003eReview current lot documents for composition and the tests performed.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eCompare formulation as well as vial count when selecting a laboratory solution. Package volume alone does not establish composition, compatibility, or suitability for a particular method.\u003c\/p\u003e\u003ch3\u003eReceiving and laboratory use\u003c\/h3\u003e\u003cp\u003eInspect both containers and their closures on receipt. Use your laboratory's validated procedures to assess compatibility and stability. Endotoxin or microbial-limit results alone do not establish sterility.\u003c\/p\u003e\u003cp\u003eContact \u003ca href=\"\/pages\/contact-us\"\u003eBulk Peptides support\u003c\/a\u003e for product documentation. Our \u003ca href=\"\/pages\/how-to-read-peptide-coa\"\u003eguide to reading a Certificate of Analysis\u003c\/a\u003e explains how to match an analytical report to its material.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research only.\u003c\/strong\u003e Not for human or veterinary use, consumption, diagnosis, treatment, or clinical application.\u003c\/p\u003e","brand":"Bulk Peptides","offers":[{"title":"2 x 10 ML","offer_id":51303744602279,"sku":null,"price":30.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/reconstitution-solution-10ml-2-pack.png?v=1788660811"},{"product_id":"lipo-c-with-b12","title":"Lipo-C with B12 10ml","description":"\u003ch2\u003eLipo-C with B12 10mL Research Solution\u003c\/h2\u003e\u003cp\u003eLipo-C with B12 is a multi-component laboratory solution supplied in a nominal 10mL vial. Compare the complete specification below when selecting this formulation; the Lipo-C name is also used for mixtures with different ingredients and amounts.\u003c\/p\u003e\u003ch3\u003eProduct specification per mL\u003c\/h3\u003e\u003ctable\u003e\n\u003ccaption\u003eLabeled formulation amounts per mL\u003c\/caption\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth scope=\"col\"\u003eComponent\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eAmount per mL\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-carnitine\u003c\/td\u003e\n\u003ctd\u003e20mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eL-arginine\u003c\/td\u003e\n\u003ctd\u003e20mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMethionine\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInositol\u003c\/td\u003e\n\u003ctd\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCholine\u003c\/td\u003e\n\u003ctd\u003e50mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6 (pyridoxine)\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B5 (dexpanthenol)\u003c\/td\u003e\n\u003ctd\u003e25mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12 (cyanocobalamin)\u003c\/td\u003e\n\u003ctd\u003e1mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThese are the stated product-specification amounts. They are distinct from measured results on an analytical report, which covers only the sample and tests it identifies.\u003c\/p\u003e\u003ch3\u003eSelect the correct Lipo-C formulation\u003c\/h3\u003e\u003cp\u003eMatch the ingredient list, nominal vial volume, and lot information to your laboratory specification. Compare this item separately from \u003ca href=\"\/products\/lipo-c\"\u003eLipo-C\u003c\/a\u003e and \u003ca href=\"\/products\/lipo-c-fb\"\u003eLipo-C (FB)\u003c\/a\u003e; their formulations should not be treated as equivalent.\u003c\/p\u003e\u003ch3\u003eDocumentation and handling\u003c\/h3\u003e\u003cp\u003eRequest the applicable formulation and analytical documents before ordering when your method depends on a particular component or concentration. Assess storage, stability, and compatibility through your laboratory's validated procedures.\u003c\/p\u003e\u003cp\u003eContact \u003ca href=\"\/pages\/contact-us\"\u003eBulk Peptides support\u003c\/a\u003e for product documentation. Our \u003ca href=\"\/pages\/how-to-read-peptide-coa\"\u003eguide to reading a Certificate of Analysis\u003c\/a\u003e explains how to match an analytical report to its material.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research only.\u003c\/strong\u003e Not for human or veterinary use, consumption, diagnosis, treatment, or clinical application.\u003c\/p\u003e","brand":"Bulk Peptides","offers":[{"title":"10 ML","offer_id":51303744667815,"sku":null,"price":84.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/lipo-c-with-b12.png?v=1788660811"}],"url":"https:\/\/bulkpeptides.org\/collections\/research-support-compounds.oembed","provider":"Bulk Peptides","version":"1.0","type":"link"}