{"product_id":"vitamin-b12","title":"Vitamin B12","description":"\u003ch2\u003eVitamin B12 Research Compound\u003c\/h2\u003e\u003cp\u003eVitamin B12 is available as a laboratory research compound, with the current product description identifying methylcobalamin. Check the listed presentation and the documentation relevant to your analytical requirements.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003cp\u003eSelect from the presentations shown on this page. For a specific batch or analytical requirement, contact \u003ca href=\"mailto:support@bulkpeptides.org\"\u003esupport@bulkpeptides.org\u003c\/a\u003e for available product documentation before ordering.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003cp\u003eMethylcobalamin is a specific form of Vitamin B12 with the molecular formula \u003cstrong\u003eC₆₃H₉₁CoN₁₃O₁₄P\u003c\/strong\u003e. Structurally, it consists of a corrin ring surrounding a central cobalt ion. In this specific configuration, the ligand attached to the cobalt is a methyl group, distinguishing it from other forms like Cyanocobalamin or Hydroxocobalamin. This structural difference allows Methylcobalamin to participate directly in methyl-group transfer reactions without the need for metabolic conversion.\u003c\/p\u003e\n\u003cp\u003eScientific interest in Methylcobalamin centers on its role as a cofactor for the cytosolic enzyme methionine synthase. This enzyme is responsible for catalyzing the remethylation of homocysteine to methionine, an essential amino acid. By modulating this pathway, researchers investigate the compound’s influence on cellular DNA synthesis and the regulation of homocysteine levels, which are markers often associated with vascular and endothelial health in research models.\u003c\/p\u003e\n\u003cp\u003eIn neurobiological research, Methylcobalamin is studied for its potential effects on the nervous system. Animal studies have explored its involvement in the synthesis of neuronal lipids and the maintenance of the myelin sheath. Furthermore, investigations utilize this compound to observe its impact on nerve regeneration and axonal transport in models of peripheral neuropathy.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eZhang, Y., et al. (2013). “Methylcobalamin: A Potential Vitamin of Pain Modulation.” \u003cem\u003eNeural Plasticity\u003c\/em\u003e, 2013, 424651.\u003c\/li\u003e\n\u003cli\u003eTakahashi, K., et al. (2005). “Methylcobalamin increases Erk1\/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model.” \u003cem\u003eExperimental Neurology\u003c\/em\u003e, 192(2), 289-299.\u003c\/li\u003e\n\u003cli\u003eWolffenbuttel, B. H. R., et al. (2019). “The Many Faces of Cobalamin (Vitamin B12) Deficiency.” \u003cem\u003eMayo Clinic Proceedings: Innovations, Quality \u0026amp; Outcomes\u003c\/em\u003e, 3(2), 200-214.\u003c\/li\u003e\n\u003c\/ol\u003e\u003c\/section\u003e","brand":"Bulk Peptides","offers":[{"title":"10 MG","offer_id":51303542980775,"sku":"B1210ML","price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0770\/0384\/9895\/files\/vitamin-b12.png?v=1788658160","url":"https:\/\/bulkpeptides.org\/products\/vitamin-b12","provider":"Bulk Peptides","version":"1.0","type":"link"}